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Metal contamination is a major prolem for the pharmaceutical and fine chemical industries. A large amount of time and resource is spent purifying compounds after catalytic steps, so that the matal cancentration in within the acceptable limit. Generally, the acceptable limit is 0.05-10 ppm, for those metals that are utilized in hydrogenation. Scavenger resins are often used for matal contamination purification. In this application note, we will demonstrate how the H-Cube and a scavenger cartridge（ScavCartTM）may be combined to perform a reaction and purification in 1 step.

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